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Stability testing is an essential part of the drug development process—maintaining the quality of active pharmaceutical ingredients (APIs) and drug products, while providing accurate shelf life. Stability testing enables pharmaceutical companies to determine the most suitable packaging and/or container closure systems for drug product storage and distribution. "Stability storage and testing play an important role in drug development from discovery to commercialization and beyond," said Scott Jedrey, Director of Quality Operations at Alcami. “With testing at each stage, whether physical or chemical, data can be collected, trended and reviewed. Based on this data, a decision is made whether to move on to the next stage, which includes more testing and more patients for clinical trials "Products must have purity, potency and safety at every stage of the drug development process in order to receive very important agency approvals." There are several important factors to consider when designing and conducting stability studies, with safety, quality and product efficacy being the most important. Drug development companies have the ability to identify and trend shelf life and its impact on efficacy by exposing samples to various temperatures, humidity levels, and light over time. Analytical methods for valid Stability Chamber testing vary by drug product. The design of a stability study must consider product form, container type, and packaging. For example, commercially released products have been tested to study the effect of conditions on the drug product and packaging container on degradation. In the case of a multi-dose product, in-use stability testing can be used. The purpose of an in-use stability study is to simulate the use of the product in practice, taking into account the fill level of the container, any dilution/reconstitution prior to use, holding time prior to use, and various diluents that may be used. for management. Degradation factors, including physical, chemical, and microbial causes, are important to study. Physical factors include changes in the physical properties of the drug, such as appearance, properties, hardness, friability, and particle size found in tablets, capsules, and semisolids. From a chemical point of view, scientists want to separate compounds into elements, simpler compounds, or change the chemical properties of drugs through hydrolysis, oxidation, isomerization, polymerization, or photodegradation. Understanding all the ways in which a finished product or API may be affected by degradation is critical to successful stability testing. For example, Stability Lab studies aim to simulate climate impacts. These studies are based on a variety of product factors, such as expected mode of transport, environmental temperature and humidity test chamber exposure to light and atmosphere, and distribution location. From these studies, scientists are better able to determine the shelf life of drugs, decide the best way to store them, and ultimately help keep consumers safe. Finally, microbial contamination of the product, depending on the type of microorganism and its level of toxicity, may also play a role in the design and function of these studies. Summarize The quality of APIs and pharmaceutical products can be safeguarded by determining appropriate storage, shelf life and distribution methods. Stability Chamber Manufacturer Thchamber has extensive experience in establishing stability programs at all stages of the drug product life cycle, from early stages to the need for drug stability testing.

Many applications require laboratory drying ovens to remove moisture from samples. They are a necessity in many environmental, clinical and biological laboratories and forced air and come in many different forms. This blog will explain what laboratory drying ovens are and what they are used for. Standard Drying Oven vs Laboratory Drying Oven Standard drying ovens are designed to remove moisture from the oven chamber to dry samples as quickly as possible. This type of oven brings fresh, dry air into the chamber while removing moist air. This dries the sample quickly, however, it requires an airflow system that can extract moisture from the air. Laboratory drying ovens are designed to heat samples only. This means that the oven will continuously circulate the same air around the chamber and provide heating only. Both oven options are effective and used to meet different requirements. The Importance of Laboratory Drying Ovens Laboratory drying ovens are an invaluable aspect of everyday workflow, and their use can range from simple glassware drying to complex controlled heating applications. Laboratory drying ovens provide temperature stability and reproducibility for all application needs. Gravity convection ovens work on the basis of the rising temperature distribution of warm air. These laboratory drying boxes do not use fans to actively distribute air indoors and have very low turbulence. Mechanical convection ovens use an integrated fan to actively move air from the room, creating an even temperature distribution in the room. This means optimum temperature uniformity and highly reproducible results. Uses of laboratory drying ovens Laboratory drying ovens can be used to control the temperature and keep it safe. They are also frequently used in testing and drying biological samples and in forensic laboratories to assist in the development of fingerprints. In addition, laboratory drying ovens can be used in environmental studies to dry samples before and after weighing to determine the moisture content of the samples. XCH Biomedical Laboratory Vacuum Drying Oven At XCH Biomedical, our laboratory drying ovens are designed to provide the highest level of performance and reliability in an energy-efficient, compact package and are available in benchtop or floor-standing configurations, providing greater flexibility in laboratory organization and layout . Manufactured to strict quality, assembly and design standards, our laboratory drying ovens are designed to include robust steel cabinets that are coated with epoxy powder for durability and protection. XCH Biomedical laboratory drying cabinets feature durable and easy-to-use latches. Temperature distribution throughout the oven allows full use of all shelf space, with additional shelves available on request. If you would like to know more about our laboratory drying cabinets, please contact us now for more information on vacuum oven manufacturer Thchamber.

Stability testing is a study designed to provide information on how an active pharmaceutical ingredient or finished pharmaceutical product is affected by temperature, humidity, climate and light over time. The duration of follow-up inspections, expiration dates and recommended storage conditions for active pharmaceutical ingredients are based on these data, and stability chambers are essential when conducting these studies. Stability Chamber - Survival of the Fittest Accuracy and repeatability of parameters in continuous operation, reliability and durability are the top priorities of the stabilization chamber. The solid stainless steel interior should be corrosion resistant and designed to be easy to clean. Programming must be intuitive, and calibration certificates, data loggers and validation documentation should of course be included. Basic requirements for stability chambers in the pharmaceutical industry What technical solutions are currently available to meet these requirements? What factors must I pay special attention to? What are the advantages and disadvantages of various technical solutions? This blog provides you with initial insights. 1. Temperature and humidity test chamber The temperature humidity chamber provides a quick overview of all achievable temperature and humidity values. The performance range of different stabilization chambers varies widely. For example, some models satisfy the conditions of five climatic zones I to IVb in addition to all the climatic conditions specified in the ICH guidelines. Such models are very generic and can be combined with each other as generic backups if desired. Other models only simulate certain climatic conditions, so their application is very limited. 2. Horizontal or vertical airflow With horizontal airflow, the air spreads evenly on each shelf regardless of the shelf's position in the stabilization chamber. Optimum temperature and humidity distribution is achieved when loading the chamber. This is especially true in the case of double-sided horizontal airflow. In the case of vertical airflow, i.e. from bottom to top, the air diffuses through the shelves, starting at the bottom, going up the middle, and finally reaching the top shelf. Each shelf basically blocks air distribution. 3. Humidifying water It's not just the type of humidification that matters - the water supplied to the stabilization chamber must also be of good quality. Connecting to an on-site water supply and drainage facility is one option, while using bulk tanks to supply fresh water and collect wastewater directly in the stabilization chamber is another option. The latter option allows the chamber to be installed away from the on-site water supply. In both cases, the ion exchanger will prepare the fresh water to the desired quality. 4. Continuous operation The stability chamber operates continuously for more than 8,000 hours per year. Robust designs, durable materials and components developed for maximum reliability are the foundations, ensuring these demanding operating times will last for years. In order to minimize the risk of time-consuming cross-contamination and stabilize indoor biocontamination, an easy-to-clean interior is absolutely necessary. High-alloy stainless steel, removable shelves, steam humidification and the absence of synthetic materials inside are just some of the key aspects. Some models also have an extended temperature range of up to 100°C, which means sterilization is possible. 5. Programming and Documentation An important factor regarding approval applications is the availability of complete and end-to-end documentation of all relevant parameters for each operational state. Needless to say, calibration certificates for temperature, climate, data loggers (process documentation independent data records), and verification documents with IQ (Installation Qualification), OQ (Operational Qualification) and PQ (Performance Qualification). If you have any questions about our stability chamber, you are welcome to contact us at thchamber.com.

With the development of people in the fields of military, aerospace and navigation, many equipment will work in high temperature, temperature and humidity test chamber. In this environment, equipment will face greater challenges. The stability of the equipment has an important influence on the operation of the equipment. The high and low temperature humidity test chamber (hereinafter referred to as the high and low temperature humidity test chamber) is used to test the performance of materials in aerospace and marine products under high temperature, damp heat and other environments. Its structure and working principle have certain particularities. 1. Use a high and low temperature test chamber Before conducting environmental experiments, it is necessary to master the properties, experimental procedures, experimental conditions and experimental techniques of the tested samples. At the same time, it is necessary to master the use technology of the equipment, clearly understand the structure of the equipment, especially the performance and operation of the controller. At the same time, the staff must read the operation manual in detail many times to avoid operation errors, which will cause the equipment to fail to operate normally, cause errors in the test data, and damage the samples during the test. In order to ensure the accuracy of the experimental data in the experiment, it is necessary to select reasonable equipment for the experiment. The selection of high and low temperature humidity chambers should be determined according to the actual conditions of the experimental samples. The volume between the laboratory and the test subject should always be in a reasonable ratio. When conducting experiments on the heated sample, its volume should be less than 10% of the effective volume of the experimental calibration. The proportion of the unheated test sample to the effective volume of the laboratory should be 20%. The location of the sample should not cause the air outlet and air outlet to be blocked, and at the same time, keep a certain distance from the humidity sensor to ensure that the temperature is normal during the experiment. The following points should be paid attention to in the use of high and low temperature humid chambers: (1) During use, ensure that the high and low humidity heating box is safely grounded to avoid casualties caused by electrostatic induction. (2) Do not touch the box with your hands during operation. (3) Unless the chamber door cannot be opened due to special reasons during the operation of the equipment, the following adverse consequences may occur: 1) The temperature inside the door is still very high 2) High temperature and high humidity will flush out of the chamber. 3) High temperature may cause fire alarm. 4) Lighting should be turned off unless necessary. 5) Try to avoid repeated opening within 15 minutes during use. 6) When the high and low temperature humidity box is running at low temperature, it is best to dry the equipment at 60°C for 30 minutes, and then open the door to prevent the evaporator from freezing or affecting the measurement time of subsequent experiments. 7) During operation, in order to ensure the safety of equipment and operators, over-temperature protectors and circuit breakers should be checked regularly. 8) In addition to full-time personnel, professional electricians are also required to participate in the maintenance and inspection of the equipment. 2. Repair and maintenance of common problems Frequently asked questions about maintenance of high and low temperature and humidity chambers During the high temperature test, if the test temperature does not reach the temperature value required by the test, the electrical system should be checked and the cause of the failure should be eliminated one by one. If the temperature rises slowly, check the air circulation system and observe the opening status of the adjustment plate in the air circulation system. If the temperature rises too fast, the rotation of the air circulation channel needs to be detected. If the temperature rises too fast, the PID tuning parameters need to be adjusted. If the temperature rises directly to the over-temperature protection, it can be concluded that the controller is faulty, and the control instrument should be replaced in time. When the low temperature does not meet the experimental requirements, it is necessary to observe the temperature change. Whether the temperature rises after falling to a certain value or whether the temperature drops slowly. The former is generally caused by the harsh environment of the drying equipment. The location and ambient temperature of the equipment should be observed. If it cannot meet the working requirements of the equipment, it should be adjusted in time. If the latter, the equipment should be checked to see if the laboratory is dry before low temperature testing. If the workshop is dry, put the test samples into the laboratory, and check whether there are too many samples stacked in the laboratory, which causes the laboratory ventilation cycle to fail to meet the requirements. 2.2 Equipment maintenance content The main contents of equipment maintenance include preventive maintenance and predictive maintenance. Of the two types of preventive maintenance, the maintenance that needs to be done once a week includes cleaning the drip tray and the laboratory body for condensed water. Maintenance required by customers in special areas includes: cleaning humidification water pipes, flushing systems or medium cooling water pipes. Maintenance that needs to be done every six months includes cleaning the air cooling equipment (condenser), maintenance that needs to be done every year, cleaning the scale inside the humidifier, cleaning the AC (high current) contactor for maintenance of the electrical control cabinet. At the same time, the lubricating oil used by the compressor should be replaced every 2-3 years. Predictive maintenance mainly includes weekly maintenance, monthly maintenance and quarterly maintenance. Weekly maintenance includes: checking the balance pressure and suction and discharge pressure of the compressor, checking the color of the oil in the compressor, and checking the oil body. Monthly maintenance included. Check the compressor discharge and suction temperatures, the liquid mirror and discharge temperatures in the condenser, and the temperature difference between the incoming and outgoing water in the cold water pipe. Check the heating rate and cooling rate of the device. Check the operating current of the compressor motor quarterly. Regular maintenance of the equipment can not only improve the stability of the equipment during operation and the accuracy of the experiment, but also prolong the service life of the equipment to a certain extent. Therefore, attention should be paid to the maintenance of high and low temperature humidity chambers in the future. 3. Conclusion Environmental Chamber Manufacturer is a special refrigeration equipment, its use, maintenance and repair should start from refrigeration, electrical control, thermal engineering and so on. In the process of use, attention should be paid to the usage specifications. When repairing, the faults that may be caused by the operation should be eliminated first, and then the faults existing in the equipment itself should be repaired. After the equipment fails, it should be repaired on the basis of mastering the structure and working principle of the equipment. In addition, the maintenance of the equipment must be carried out on time, and the maintenance of the equipment cannot be ignored because the equipment has not failed for a period of time.

How do you determine the right lab drying oven for your lab and application? With so many lab ovens on the market, how do you find the perfect oven for your needs? Here are some tips to help you: 1. Select the oven type according to your application. Mechanical convection drying oven Designed with a motor and fan to circulate air for even heating and faster drying times - ideal for drying and heating of samples requiring greater accuracy, multiple samples and high moisture content. Application General Heating - Baking, heating and drying glassware and rubber Sophisticated Heating - Bitumen testing, conditioning, digestion of proteins and starches, drug metabolism, electronic aging, epoxy and plastic curing, serum protein analysis, stability chamber and QC batch testing, sterilization, suspended solids assessment and vulcanization studies. Gravity Convection Drying Oven No need for a fan to ensure gentle, natural circulation of the warm air moving upwards - ideal for disinfection, drying and other applications requiring subtle airflow. Application Use when the powder or substance will be disturbed by the airflow generated by the fan. Ideal for simple heating such as baking, drying, conditioning, preheating, aging and curing. Vacuum drying oven A vacuum is created to remove moisture from the sample faster than using ambient temperature. Ideal for tightly controlled processes such as drying, vacuum embedding, electroplating and semiconductor processing. Application Heat in an oxygen-free atmosphere to prevent sample corrosion or scaling. Drying, low temperature drying, aging testing, moisture determination and chemical resistance studies. Ideal for pharmaceutical/food drying and electronics Plant vacuum oven Provides higher vacuum levels for faster and safer extraction. Great for botanical and cannabis applications. 2. Match the oven size to your material. Choose an oven that is neither too small nor too large. Consider the size of the sample and how many you need to put in the oven at one time. Choose a smaller one that might fit your space but not your sample. Getting the maximum oven when you don't need it will consume too much energy and you will lose cost efficiency. 3. Use the oven at your desired temperature. Maximum oven temperatures range from hundreds to thousands of degrees. Choose the oven temperature based on the desired temperature for your materials. Like size, you don't want to choose a size with a higher temperature range if you don't need it. You will waste money and energy. 4. Choose the oven with the best thermal insulation. Lab ovens often run at high temperatures for long periods of time and consume a lot of electricity. Choose an oven with the best thermal insulation to reduce heat transfer rates. This will prevent the generated heat from leaking out of the chamber, minimizing energy waste and saving energy costs. 5. Look for ovens that are easy to clean and maintain. Being able to clean and maintain your oven is very important. Failure to do so could undermine the lab's push to advance your science. Look for ovens with rounded corners for easy cleaning, and stainless steel components and interior construction to extend the life of your oven. Also, look for trays and racks that can be removed quickly, as well as a larger door so you can access the inside of the oven when you need to clean it. A leak has occurred. 6. Make sure the oven you choose has reliable safety features. Prevent fire and protect your valuable samples from overheating. Choose an oven with a built-in over-temperature thermostat so that if the temperature exceeds a set temperature, the oven will shut down. Other features to consider include temperature excursion alarms, overcurrent protection, and automatic start-up after power loss/recovery.

Which should I buy, Walk-in or Reach-in Stability Chamber? Many pharmaceutical manufacturers will ask this question. The name of the Stability Chamber tells you the difference, and the following points will add details. Let's treat it as pros and cons. XCH Biomedical Walk-in Stability Chamber Advantage Virtually unlimited size, so lots of shelf space/samples can be accommodated One Qualification Covers a Lot of Shelf Space Conditions in the Walk-in Stability Chamber tend to be more stable due to their larger size Shortcoming Faulty chambers can cause problems with large numbers of samples They are fixed. (XCH Biomedical can provide crane lifting support for some walk-in rooms) Installation often requires architectural, electrical and refrigeration skills Compressors add footprint or remoteness and therefore cost Identification requires additional probes Spare parts may vary by special build They usually require 3-phase power and an additional water supply Operator time indoors may be limited for safety reasons Siloed space is a necessary waste of footprint Reach-in Stability Chamber Photostability Test Chamber Advantage Can be easily delivered in one piece small footprints Can be moved easily, with casters as standard If one Reach-in Stability Chamber fails, the sample can usually be accommodated in the other Reach-in Stability Chamber Cold room service is easier, faster and cheaper due to smaller refrigeration system Since they are "off the shelf" or "series" products, spare parts are usually in stock They are single-phase powered They have no island space no lighting required They are usually in stock and available for urgent sale or rental Shortcoming Size is usually limited to 2000 liters Each unit must be individually qualified Conditions are slightly less stable than Walk-in Stability Chamber, but still several times better than ICH stability test limits. In conclusion So, as we can see, there are pros and cons between the two. We hope you find this information useful and that it will help you decide which is the best option for you, Walk-in or Reach-in Stability Chamber. Of course, this may also depend on budget, space and long-term plans, but if you would like to discuss further or have any questions, please do not hesitate to contact us.

Stability chamber are used to test products and evaluate their shelf life, such as electronic components, industrial accessories, pharmaceuticals, etc. It enables researchers to modify parameters such as humidity and temperature for rigorous examination under various conditions. There is no doubt that various products require different test conditions, but it is practically impossible to roam around to experience different climatic conditions. This is where stability chambers come in handy to make researchers' jobs easier. With these systems, researchers can track changes in product quality under alternating environmental exposures. Types of Stability chambers Generally, there are two types of Stability chambers: Reach in Chambers: They are small and used to test small quantities of products. One of the main benefits of using these chambers is their convenience. Walk-in rooms: As the name suggests, these rooms are larger in size and you can walk in. They are used to test high-volume projects that require precise conditions over long periods of time. Walk-in test chambers are used to record product performance under the following conditions: wet/wet conditions rain arid area exposed to the sun elevated temperature conditions significant environmental change Besides these two, there are other types of rooms, although not very popular in the real world: a) Environmental Room b) Accelerated laboratory c) Temperature and humidity chamber d) Photostability Chamber The function of the stability chamber The working of these chambers is based on the simple principle that by maintaining a standard temperature, a stable value of relative humidity will also be maintained. Simply put, relative humidity is the ratio of the current water in the air to the optimum it can be kept in. When the temperature increases, the capacity of the water that the air can hold increases. At the same time, the relative humidity is significantly reduced. In this way, both parameters are modified at the same time. All Stability chambers comply with the ICh regulations, which stipulate that the temperature deviation must not exceed 2 to 3 degrees and the humidity change must not exceed 5%. The inner and outer bodies are made of corrosion-resistant stainless steel. The inner body is also lined with a suitable insulating layer. The chamber includes a number of shelves for items that can be quickly removed. Sensors are attached to these chambers to identify temperature and humidity levels. Horizontal laminar airflow is the preferred solution to more accurately homogenize the desired conditions. With this system installed, they will receive consistent airflow even when racks are full of samples. The presence of an additional blower maintains proper circulation of the air. Data loggers are also used to receive and transmit information. Application of Stability Chamber Stability chambers have a wide range of uses. They are critical when completing the manufacture of a specific product. Therefore, it has a wide range of uses in the automotive industry, pharmaceutical industry, packaging, cosmetic industry, research work, biological or microbiological testing, etc. There are various types of Stability chambers on the market. However, you need to choose the right one according to your needs. If there is any guidance, it is advisable to consult an expert rather than make all decisions yourself. Do you want to purchase a high quality Stability chamber for all your research needs? If you feel that way, then Stability Chamber Manufacturer thchamber.com is the place for you.

Vacuum oven manufacturer Thchamber laboratory drying oven, is a high temperature oven that is part of the equipment in most clinical, forensic, electronic, material processing and research laboratories. Laboratory drying ovens provide uniform and precise temperature control for functions such as heating, baking, evaporation, drying, sterilization and other industrial laboratory functions. Laboratory drying oven temperatures typically range from ambient to over 200°C, meeting laboratory requirements for temperature uniformity, stability and accuracy, advanced protocol ovens can be used to meet such demanding requirements. Laboratory Drying Oven Applications and Industries Laboratory ovens or drying ovens are used in a wide range of applications in industries such as biotechnology, pharmaceuticals and materials manufacturing. These industries often require the process of baking, curing, annealing and drying materials with different chemical and physical compositions. The end results of many of these process applications are unique and thus require various types of laboratory ovens. Lab Drying Oven The following functions are available, depending on the process required by the application. Annealing The annealing process involves heating and then slowly cooling a material such as glass or steel to reduce internal stress and increase ductility. High temperature ovens are used in this process, commonly used in the metallurgical, medical device manufacturing and materials science industries. Annealed material can be cut and shaped more easily for the production of items such as syringes and catheters. Conservation Curing involves hardening the chemical composition of a substance through a combination of drying and baking. The process is commonly used in polymer research, nanotechnology and the manufacture of epoxy resins, glues, plastics and rubbers in the semiconductor industry. Drying Drying is the removal of moisture from a sample, which is necessary for many environmental, biological, and clinical laboratories. Forced air and laboratory vacuum oven are used to dry easily decomposed samples because they remove moisture and lower the boiling point of water, allowing samples to dry at lower temperatures. Sterilize Sterilization involves the removal of bacteria or microorganisms and is often used to sterilize laboratory equipment. Laboratory ovens can be used to sterilize laboratory equipment and glassware. The ideal temperature needs to be at least 160°C and monitored at this temperature for 45 to 60 minutes. A slow cooling period is then required, as removing items directly from the oven can cause them to crack, while gradual cooling prevents potentially harmful air from entering the oven. These items then need to be dried using a temperature of 60°C.

A laboratory incubator is a critical piece of equipment in any laboratory. By regulating conditions such as temperature, humidity, and carbon dioxide, they provide a controlled, contamination-free environment for safe, reliable operation of cell and tissue cultures. What is a laboratory incubator? It is a heated insulated box used to grow and maintain microorganisms or cell cultures. Laboratory incubators do this by maintaining the optimum temperature, humidity and gas content of the internal atmosphere. Incubators vary in size from compact table top units to larger systems (cabinet size). The simplest incubators offer only a little, a little more than a temperature-controlled oven, which is capable of reaching temperatures of 60 to 65°C, but is usually used around 36 to 37°C. Plenty of modern incubators can also generate refrigerated temperatures and control humidity and carbon dioxide levels. What is the use of a laboratory incubator? The main function of an incubator is to provide a controlled, contamination-free environment for cell and tissue culture by regulating conditions such as temperature, humidity, and carbon dioxide for safe and reliable cell and tissue culture. Laboratory incubators are the basis for growth and storage of bacterial cultures, cell and tissue cultures, biochemical and hematological research, pharmaceutical work and food analysis. Typically deployed in modern research laboratories, incubators maintain a stable atmosphere for processes such as cell and microbial culture, and antibody and cell culture for fluorescence microscopy. A common misconception is that ovens can be used in place of incubators, as they both generate heat. They are not the same, however, as ovens typically produce temperatures between 93.3 and 316 degrees Celsius, while incubators typically produce temperatures between 15.6 and 48.9 degrees Celsius. Therefore, an oven cannot be used as an incubator, as most ovens are not warm enough to be used as an incubator. Incubators are used for the cultivation of cell cultures, bacterial colony propagation and bacterial counts in the food industry, bacterial colony propagation and subsequent determination of biochemical oxygen demand in wastewater monitoring, propagation of microorganisms such as bacteria, fungi, yeast or viruses; in zoology Insect reproduction and egg hatching, controlled sample storage and crystal/protein crystal growth. In conclusion, laboratory incubators play a vital role in laboratory settings. If you want to buy laboratory incubators at the best price, explore the widest range of laboratory incubators, mould incubators, heated incubators and bacteria incubator at Thchamber.

If you need a incubator lab equipment, you'll undoubtedly be frustrated if it doesn't work. If your device doesn't heat up or cool down at all, or doesn't reach its set temperature, a number of factors could be at play.   In this article, we'll help you troubleshoot by looking at some of the possible causes of temperature problems in your lab incubator, including those that provide refrigeration.   1. There is a mechanical failure If your device doesn't heat up or cool down at all, this can be a serious problem. You may have a damaged component or controller, both of which will require repair and you may need to purchase replacement parts. You might even want to consider buying a new machine.   If your lab incubator is cooling, but not cooling at all, one of the most likely causes is a malfunctioning compressor. In this case, you need to repair or even replace the machine.   2. The temperature protection setting is too low or too high Over-Temperature Protection (OTP) is a handy feature found in many laboratory incubators. It acts as a backup by turning off the heat (and sometimes activating a visual or audible alarm) in case the temperature spikes for some reason. This helps ensure that sample integrity and stability are not compromised by excessive temperature.   Most temperature control devices with this feature use over and under temperature alarms. Predictably, under-temperature protection (UTP) is the exact opposite of OTP. You set a minimum temperature to avoid exposing your samples to excessive cold. If this setting is higher than the set value, your device will not cool to the desired temperature.   3. The temperature needs to be stable In some cases, your machine may appear to be heating up or cooling down, but the temperature on the reference thermometer does not match the primary temperature control reading.   One of the most likely reasons is that the temperature has not stabilized. If the door has recently been opened, the appliance has been turned off, or the temperature has been reset, there may not have been enough time for the internal temperature to stabilize.   4. Not properly calibrated In the above case, if the temperature has had enough time to stabilize, the problem may be with the calibration. If one of the thermometers is not properly calibrated, their readings will simply not match.   It is recommended that the device be calibrated at a temperature similar to your process temperature and every time you change to a new temperature.   5. The door is sealed For incubators and refrigerators, door seals can be an issue if the unit is not reaching temperature. If the seal does not work properly, air exchange will occur between the equipment and the environment, allowing hot air to escape (in the hatching unit) or enter (in the refrigeration unit).   6. Not enough free airflow For these units to work, you really need to make sure there is enough free airflow around the machine. While you don't need a lot of space, it's not a good idea to push the unit against a wall or other equipment. A few inches of "breathing room" on the sides and rear of the unit will help ensure enough free airflow for it to function properly.   For the cooling incubator, if ice forms on the evaporator, the device may not cool sufficiently. This causes insulation and makes it harder for the compressor to do its job. You can remove ice and try to limit door openings to keep moisture from entering the unit.   7. Need more power The power supply is unlikely to be an issue with the machine in an existing setup, but could be an issue in a new installation. If this is the first time you are using the unit or you have moved it to a new location, you should check that the amperage and voltage of the power supply meets the requirements of the unit. You should be able to see these numbers on the machine's nameplate.   Lab Incubator Manufacturer XCH Biomedical have BOD incubator, widely used for research and production departments such as environmental protection, sanitation and epidemic prevention, agriculture, livestock and aquatic products, drug testing, cell culture, etc. ;  The mold incubator is a special constant temperature equipment for water body analysis BOD detection, mold and other microorganism cultivation, widely used for research institutes of health and epidemic prevention, agriculture, livestock and aquatic products;  Heated incubators are used in medical and health, pharmaceutical industry, biochemistry and agricultural science and other scientific research and industrial production departments for bacterial cultivation, fermentation and constant temperature testing. Cooling incubator provides precise temperature control for reliable results in pharmaceutical, industrial testing, food, cosmetics, and microbiological research.

Battery testing is a vital component in several industries including technology, transportation, aerospace and healthcare. At its best, it drives market-changing innovation and, in some ways, sustainability. However, incorrect battery testing can put consumer safety at risk and cost your company millions of dollars. Just look at the smartphone makers that have repeatedly recalled because of exploding batteries. This situation can be avoided with accurate, repeatable testing. This can only be achieved with a high-quality temperature and humidity test chamber. These allow you to switch between extreme conditions to measure battery durability, corrosion resistance and performance. While they range in size from 1 cubic foot to 264 cubic feet (or larger) and can be customized to your needs, the optimal temperature and humidity chambers for battery testing have the same performance and physical design. Here's what to look out for when buying. Given the number of variables that affect environmental testing, materials used to construct temperature and humidity chambers need to optimize performance and maintain durability. When considering your surroundings, you must consider extreme temperatures, humidity ranges, and potentially unstable products. The top-of-the-line Constant Temperature & Humidity Chamber has the following physical design features: High efficiency, low k-factor, thermal insulation to provide a stable temperature environment in the workspace Heavy-duty steel housing protects multiple mechanical and electrical systems from laboratory and production line elements This combination ensures accurate test results and can withstand repeated testing (as long as the chamber is calibrated regularly). You can extend the life of your test chamber beyond 15 years if you follow a regular monthly, quarterly and yearly maintenance schedule. As for performance, battery tests are typically held in a temperature range between -20 and +120 degrees Celsius. You'll find Thchamber JSB temperature and humidity chamber offers a standard range of -40 to +150 degrees Celsius. XCH JSB High And Low Temperature Humidity Chamber is through the test and detection, so as to judge whether the performance of the product meets the design requirements for testing. The criteria you test against will determine your performance needs, although it won't make any sense if the results are inaccurate. The best temperature and humidity chambers maintain accurate temperatures within 0.5 degrees Celsius and relative humidity within 2%. Fluctuations larger than those can jeopardize your data and may require further testing. Remember, finding a temperature and humidity chamber should be a collaborative effort. Consult your researchers and engineers and work with environmental chamber manufacturers with the expertise to customize solutions for you.

You may have come across terms such as environmental chambers, climate chamber, and test chamber. But what's the difference between these and which one is best for your testing needs?   In fact, these terms are interchangeable without any meaningful difference. Although an environmental chamber is probably the most commonly used term, the most important difference is determining which type of environmental testing is best for your needs. Environmental chambers need to meet a wide range of requirements, push the devices under test to their physical limits, and simulate all the real-world conditions they may encounter.   Temperature test chamber Designed to give engineers the precise control they need for temperature cycling or steady state testing, temperature chambers are used to test medical devices, pharmaceuticals, vaccines, electronics, batteries (with adjustable grips for different battery types), military and defense, communication, transportation, etc.   Constant Temperature Chamber rely on complex heating systems to ensure reliable test conditions and industry standards. Performance chambers typically have a range of -70°C to 180°C (-94°F to 356°F), while those designed for stability testing are 201°F). They come in a wide range of volumes, from benchtop models less than 1 cubic foot to walk-in rooms.   The airflow design of the chamber enables the fast-reacting heater to maintain tight control of the temperature inside the chamber to an accuracy of ±0.5°C.   The Constant Temperature Chamber also has an air-cooled or water-cooled system.   While air cooling costs less, its pull down is generally slower than water cooling options. Alternatively, water cooling units are more efficient but more complicated to install and require a permanent source of water. You can further enhance cooling by integrating liquid nitrogen (LN2) or carbon dioxide (CO2) into the system. These contribute to faster pulldown rates.   Regarding safety features, the temperature chamber has an adjustable high/low control that prevents the temperature from rising or falling below a certain limit during testing. In addition, these chambers benefit from internal high temperature safety features and a refrigeration system with overvoltage safety circuits.   All of these components combine to create an environmental test system that identifies leading-edge technology for durability and safety.   Temperature humidity test chamber In addition to temperature, many standards also require humidity components. Humidity chambers, similar to temperature chambers or thermal chambers, range in size (from bench-top to walk-in models) and performance.   They rely on steam generator systems to create and tightly control humidity conditions in the workspace.   These steam systems consist of closed stainless steel or copper pipes. Another component then heats the water that turns into steam or steam and passes through the tubes, where it combines with the conditioned air in the plenum before entering the interior workspace.   A standard humidity chamber will accommodate test conditions between 20% and 95% relative humidity (RH), which is the amount of humidity achievable at a given temperature. For example, a RH of 5 degrees Celsius is very different from an RH of 32 degrees Celsius. For those requiring more extreme RH levels, high humidity sensors can achieve up to 98% relative humidity, while desiccant air dryers can achieve as low as 5% relative humidity.   Thchamber has been designing, building and stability test chambers for many years. Get in touch today to learn more about how environmental testing can enhance your product line or help you meet industry standards.