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  • How to Determine the Accuracy of Temperature and Humidity in a Stability Chamber
    Mar 15, 2023
    A stability chamber is an essential piece of equipment in many industries, especially those involved in pharmaceuticals, food, and electronics. It is used to test the stability of products and ensure they meet the required standards over time. The accuracy of temperature and humidity within the chamber is crucial to ensure the validity of the test results. In this article, we will discuss how to determine the accuracy of temperature and humidity in a stability chamber. Calibration The first step in determining the accuracy of a stability chamber is calibration. Calibration is the process of comparing the readings of the stability chamber to a known standard. This is done by using a calibrated thermometer and hygrometer. The calibration should be performed at least once a year, or more often if required by industry regulations or company policy. Check the Placement of Sensors The placement of the sensors in the humidity and temperature controlled chamber is critical to obtaining accurate readings. The sensors should be placed in a representative location that reflects the temperature and humidity of the entire chamber. The sensors should not be placed near any heat sources or vents, which can affect their readings. Monitor the Stability Chamber Continuous monitoring of the stability chamber is necessary to ensure that the temperature and humidity remain within the required range. The stability chamber should be equipped with an alarm system that alerts personnel if the temperature or humidity goes outside the specified range. Perform Qualification Tests Qualification tests are designed to verify that the stability chamber is working correctly and consistently over time. The tests include temperature mapping, which involves placing temperature sensors throughout the chamber to ensure that the temperature is consistent throughout. Additionally, a humidity mapping test can be performed to ensure that the humidity is consistent throughout the chamber. Document the Results It is essential to document the results of all tests performed on the stability chamber. This documentation should include the date of the test, who performed the test, the equipment used, the results, and any corrective actions taken if necessary. In conclusion, the accuracy of temperature and humidity in a stability chamber manufacturer is crucial to ensure the validity of test results. By performing regular calibration, monitoring the stability chamber, performing qualification tests, and documenting the results, you can ensure that your stability chamber is accurate and reliable.
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  • Stability Chamber Solutions in Laboratory
    Mar 07, 2023
    Stability Chamber are critical settings for research, testing, and analysis. However, maintaining a stable laboratory environment is essential for achieving accurate and reliable results. Factors such as temperature, humidity, lighting, air quality, and equipment calibration can all affect experimental outcomes. In this article, we will explore some solutions to ensure a stable laboratory environment. Temperature and Humidity Control Humidity environmental test chambers are crucial for maintaining stable conditions in a laboratory. High or low temperatures and humidity levels can negatively affect the quality of samples, the accuracy of instruments, and the reproducibility of experiments. Therefore, it is important to monitor and control these variables. Air conditioning systems, dehumidifiers, and humidifiers can help regulate the temperature and humidity of a laboratory. Lighting Lighting is another factor that can impact laboratory stability. Natural light, fluorescent lights, and other types of lighting can interfere with experiments and alter results. To minimize the effects of lighting on experiments, laboratories can use LED lighting, which emits less heat and radiation, and install light-tight curtains to block out natural light. Air Quality The quality of the air in a laboratory can also impact the accuracy of experiments. Airborne particles, such as dust, bacteria, and chemicals, can contaminate samples and alter results. Therefore, laboratories should have proper ventilation systems, air filters, and fume hoods to remove contaminants from the air. Equipment Calibration Proper calibration of laboratory equipment is critical for obtaining accurate results. Over time, equipment can drift from its original calibration, leading to errors in data. Laboratories should have a regular calibration schedule to ensure that equipment is functioning correctly. Regular Maintenance Regular maintenance of laboratory equipment and facilities can prevent breakdowns and ensure that experiments are conducted with consistency. Laboratories should have a maintenance plan in place that includes regular cleaning, equipment checks, and repair or replacement of any faulty equipment. Conclusion In conclusion, a walk in environmental chamber is essential for accurate and reliable results. Temperature and humidity control, lighting, air quality, equipment calibration, and regular maintenance are all critical factors to consider when ensuring a stable laboratory environment. By implementing these solutions, Stability Chamber can minimize the effects of external variables and achieve consistent and accurate results.
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  • What happens to my Stability Chamber when the lab loses power?
    Feb 28, 2023
    You may be using an environmental chamber for testing and suddenly lose power. This can be caused by something as simple as a broken power line or a more severe weather event such as a snowstorm, flood or tornado. Sudden loss of power can not only interrupt the test, but also damage your chamber. Fortunately, when your lab loses power, there are a few precautions you can take to avoid loss of power and potential chamber damage. Keep these in mind, especially when severe weather comes into the forecast for your area. When your test box loses power In the event of a power failure, your test chambers will shut down completely, as they require constant power to operate. If possible, you should disconnect the test chamber from the mains voltage as soon as possible to prevent any potential damage that may be caused by power surges when power is restored. A power outage in a room presents several dangers: The test chamber contains sensitive electrical components. Although manufacturers take precautions to protect system components from power outages, some components, such as the XChange board, can be damaged by multiple power surges. It's best to use a surge protector to prevent this from happening. Components can fail or degrade over time due to repeated power outages or power surges. Likewise, using a surge protector is a surefire way to protect the chamber and its electrical components. You also need to keep in mind the type of testing you are doing. For example, there are increased hazards when conducting battery tests. Power interruptions during battery testing increase the risk of hazardous events such as thermal runaway. Losing power mid-test also means the battery safety features will no longer work. Not only will this affect your test results, but it will leave your battery components vulnerable to damage, costing you money in the form of damaged products and delayed test times. So it's best to avoid battery testing in bad weather, or invest in a generator to keep your lab powered in the event of a power outage. Finally, remote testing techniques will not work during a power outage. This can present challenges if test room users are not in your lab when a large number of active rooms lose power. For example, you can no longer know what is going on in your room. In addition, test data may also be lost. This can be frustrating and delay your testing plans. After your test chamber is powered off Once power is restored to your chamber, it is best practice to verify that all chamber functions are working as expected. If some functions do not function properly after a power outage, please contact your manufacturer for further assistance. You should keep them on call at all times, not only for routine maintenance, but for rare situations like unexpected power outages. If you are testing while the power is out, you will usually want to restart the entire test when power is restored. However, this depends on factors such as the internal conditions of the stability test chamber prior to the outage, the duration of the outage, and the specific tests you are running. Review the testing criteria you are using to inform your recovery decision. In most cases, a change in temperature or humidity conditions will affect your test and you will need to start over. Fortunately, there are some precautions you can take to ensure that downtime is minimized and damage to your photostability chamber is avoided. Preventive measures you can take If you anticipate that severe weather may threaten your laboratory's electrical supply, disconnect your test chamber from the mains voltage. It is recommended that you suspend any testing until you are confident that the threat to the power source has passed. If you are using remote testing capabilities, the lab should have a plan and system in place to handle sudden power outages. This will vary from lab to lab, but it is recommended to have an emergency power source such as a generator and a surge protector for the lab. Otherwise, you could lose important data and run the risk of adding unnecessary wear and tear to test chamber components. To ensure your lab is well-equipped to handle potential power outages, consult a trusted manufacturer for optimal lab design. In addition to preparing you for potential power outages, reliable manufacturer XCH Biomedical will provide you with layout recommendations for increased efficiency and safety. Ultimately, if you use surge protectors and maintain emergency power, your lab should be well protected against power threats, keeping your test schedule on schedule and your test equipment safe. Environmental chamber manufacturers XCH Biomedical is an industry leading laboratory designer and manufacturer. Contact us today to learn more about what you can do to prevent power outages in your environmental chamber and what to do if this happens.
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  • Stability Test Chamber: Ensuring the Reliability of Products
    Feb 22, 2023
    Stability test chambers are specialized equipment designed to evaluate the reliability and stability of products under various environmental conditions. These chambers simulate harsh environmental conditions like high and low temperatures, humidity, and light exposure that the products may encounter during their lifecycle. This testing process is essential to ensure that the product meets the required quality standards and performs reliably throughout its intended lifespan. The stability test chamber works by providing a controlled environment where the product is subjected to different stress factors, such as temperature, humidity, and light exposure. The chamber is fitted with sensors that monitor and control the conditions inside the chamber. The sensors transmit data to a computer, which analyzes and records the results. The product is placed inside the chamber, and the conditions are varied according to the test protocol. The stability test chamber is widely used in various industries, including pharmaceutical, medical, and food industries. In the pharmaceutical industry, stability testing is required by regulatory bodies to ensure the safety and efficacy of drugs. Stability testing is also crucial in the food industry, where it is used to evaluate the shelf life of food products and their resistance to microbial growth. The photostability chamber can also be used for accelerated testing, which involves exposing the product to harsh environmental conditions to speed up the testing process. Accelerated testing is useful in situations where the product lifespan is shorter than the traditional testing period. For instance, in the electronics industry, the lifespan of electronic components is relatively short. Therefore, accelerated testing is used to determine the performance of the components under harsh conditions and predict their lifespan. Stability test chambers are available in different sizes, depending on the product being tested. Some chambers are designed for small products like pharmaceuticals, while others are designed for large products like vehicles. Like walk in stability chamber. The chambers can also be customized to suit the specific needs of the user. In conclusion, the stability test chamber is an essential tool in the product development process. It plays a significant role in ensuring the reliability and safety of products by evaluating their resistance to harsh environmental conditions. The data obtained from stability testing is crucial in making informed decisions about the quality and performance of products. It is, therefore, important for manufacturers to invest in stability test chambers to ensure the quality and reliability of their products.
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  • Why are stability test chambers important?
    Feb 13, 2023
    Stability test chamber play a vital role in ensuring the quality and safety of products. By simulating real-world storage conditions. A Stability chamber is a type of environmental chamber used in the pharmaceutical, cosmetic, and food industries to simulate and control storage conditions for products. The purpose of a stability chamber is to determine the shelf life of a product and to ensure that it remains within acceptable quality limits during its intended storage time. Stability chambers are designed to simulate different temperature and humidity conditions, and can be programmed to maintain specific conditions for extended periods of time. They typically have a temperature range of between 5°C and 60°C, and a humidity range of 20% to 80%. The temperature and humidity are monitored and controlled using sensors and actuators, and the data is recorded and analyzed to determine the stability of the product. In pharmaceuticals, stability chambers are used to test the humidity and temperature controlled chamber of drugs, vaccines, and other medical products. This is critical to ensure the safety and efficacy of these products over time, and to ensure that they remain within their shelf life. Stability chambers are used to store samples at specific conditions, and the samples are periodically tested to determine any changes in the product's quality. In the cosmetic industry, stability chambers are used to test the stability of skin care and cosmetic products. This helps manufacturers determine the shelf life of their products, and to ensure that they remain stable and effective over time. In the food industry, stability chambers are used to test the stability of food products, such as packaged food and beverages. This helps manufacturers to determine the shelf life of their products, and to ensure that they remain fresh and safe to consume over time. Stability chambers are critical to ensuring the quality and safety of products. They help manufacturers to determine the shelf life of their products, and to ensure that they remain within acceptable quality limits during storage. This helps to ensure that consumers receive safe, high-quality products that meet their needs and expectations. You can access stability chamber manufacturer to know more details.
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  • Types of Stability Chamber requirements
    Feb 06, 2023
    Stability Chambers are specialized enclosures that create a controlled temperature and humidity environment. Industries as diverse as pharmaceuticals, packaging, environmental testing and controlled storage use immersion or walk-in test chambers for stability testing. These test rooms are designed to find defects or weaknesses in products under different conditions by providing a controlled testing environment. Stability chamber qualification requirements fall under the category of installation, operation, and performance. Stability test chambers are subject to these three qualification tests before being put into operation. Stability Room Qualification Requirements To be certified to perform stability testing, an environmental chamber must go through a three-part qualification process. Qualifications must also include calibration records for all instruments used and evidence of their calibration status. The three qualification types are Installation Qualification (IQ) Operation Qualification (OQ) Performance Qualification (PQ) Together, these three stability chamber qualification requirements and tests support and document proper operation. Installation Qualification (IQ) Overview: The first qualification verifies that the stability chamber complies with its design specifications. All parts have been counted and checked for proper fit. Appropriate documentation must also be provided, including user manuals and any certifications and standard operating procedures (SOPs). Requirements: All components must be properly installed and functional for the stability chamber to pass installation qualification. If the chamber has a control panel with a human machine interface (HMI) or other guidance devices such as buttons and selector switches, they must function as designed. All alignment and safety equipment also needs to pass inspection. Operation Qualification (OQ) Overview: Run qualification tests to stabilize the room's functions and verify that systems and subsystems operate as expected within the normal operating range—including testing all doors, switches, controls, and alarms. REQUIREMENTS: The operational qualification test verifies that the temperature and humidity inside the chamber are equalized. To ensure accurate temperature and humidity readings, the operator waits a few minutes for them to stabilize, then runs the test for the specified time. Conduct Open Doors studies prior to completing operational qualifications. The test consists of opening the door for short periods of time while recording temperature and humidity at short intervals. The door opening test was repeated at least three times to calculate the average recovery time of the chamber. Performance Qualification (PQ) Overview: Performance qualification verifies that the stable chamber meets performance specifications at full load. Typically, testing is performed at the operating set point of the chamber, loading a mock product to replicate a typical environment. Measure temperature and relative humidity uniformity using thermocouples and relative humidity (RH) sensors. Requirements: The stability chamber must operate at full capacity for at least 24 hours to pass performance qualification. After the initial study is complete, the trial will be repeated with an open door study to calculate its mean recovery time. The stability laboratory qualification and performance process is conducted annually using the same procedures as past testing. After each reaccreditation, the results should be compared to previous years to track the Chamber's overall performance. XCH Biomedical Stability chambers in pharmaceutical XCH Biomedical designs and manufactures a wide range of climatic test chambers in compliance with ICH guidelines, including stability chambers, temperature and humidity chamber, walk in environmental chamber,Incubator For Bacterial Culture and vacuum drying oven. You can click to view our full product line.
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  • Considerations Needed When Purchasing a Laboratory Oven
    Jan 17, 2023
    One of the essential pieces of equipment in any materials testing laboratory is an oven, also known as a oven. They remove surface moisture while heating the material. Drying chambers are used in a variety of different applications such as sterilization, annealing, aging tests and incubation. Choosing a laboratory drying oven is an important purchasing decision. With a large number of ovens available with different configurations and characteristics, it is important to understand how to evaluate an oven based on various specifications and capabilities. How to choose a drying oven for laboratory Read on to learn five factors to consider before purchasing a lab drying cabinet. 1. Heating method On the surface, each oven works basically the same way—heating and removing moisture from samples inside. Ovens, however, accomplish this differently. Ovens utilize three heating methods: infrared (IR) heating, convection heating, or a combination of the two. Ovens that use convection heating are equipped with fans that circulate hot air around the chamber to evenly heat the sample. Meanwhile, infrared ovens allow you to target specific areas for heating. They operate by line-of-sight heating, which means they transfer heat to the part of the object that is directly within the line-of-sight of the heater. Ovens with hybrid infrared convection heating systems tend to be favorites of professionals because they offer greater drying flexibility. 2. Oven structure How an oven is constructed determines its performance. When you're examining an oven you might want to buy, there are some important structural features to look out for. First, look at the materials used. Depending on your needs, you can choose an oven made of durable, non-corrosive and easy-to-clean stainless steel. Then, look at its insulation. A well-insulated oven prevents heat loss that could damage samples. If you are performing high temperature processes, choose a double wall oven to ensure it can withstand extreme heat. Also, to avoid any heat loss, choose doors with heavy-duty doors and safety hinges for a tight seal that keeps air out. Another factor to watch carefully are the controls. The oven with digital PID (Proportional, Integral, Derivative) control is programmable for more accurate testing and includes many features such as calibration routines and data logging. You may also want an oven with overheat protection to help keep you safe in the lab. They automatically shut off if the temperature exceeds a certain point, preventing fires and accidents. 3. Chamber size How large or small is your sample size? This will help you determine the size of the oven to buy. Choosing a chamber that is too small will be a hindrance to your productivity. At the same time, a device that is too large will make your lab feel cramped and cost more due to its higher heat output. So before looking for an oven to buy, measure the available space in your lab. Take note of the width and height to get a better idea of which ovens to consider and which might not fit. 4. Heating uniformity No matter how many are placed, the samples in the oven must receive the same heat treatment. Therefore, the heat should be consistent throughout the oven. This is known as heating or temperature uniformity. Several factors can affect the uniformity of heating in an oven, primarily the way the oven is constructed. If the insulation is inconsistent or there are small gaps in the oven door, cold air can seep in and disrupt the temperature in the room. These cold spots cause some samples to get hotter than others. For example, if you place samples that are subjected to varying degrees of heat, this can result in poor product quality or inconsistent and unreliable results. That's why it's in your best interest to look for an oven that distributes heat evenly. But how do you know if it exists? Usually, reputable manufacturers will provide information about the heating uniformity of their ovens on their official product pages online. For example, on the official page for Across International's 250C 3 Shelf Vacuum Oven, you'll find it clearly states that its temperature uniformity is ±7% of set point. 5. Recovery time Whenever you open the oven door to add or remove samples some heat is released. When this happens, the oven increases energy output to compensate for heat loss. The time it takes to return to the proper temperature is the recovery time of the oven. Ovens with shorter recovery times allow for greater accuracy and thermal uniformity, but at the cost of adding more load to the system. Depending on your specific use case, this may be a negligible or non-negotiable feature. If your samples have very complex heating requirements, it is best to purchase an oven with a short recovery time. Or, if your oven has a relatively long recovery time, it can prevent excessive heat loss. Being more careful when preparing samples can help limit how often the oven door is opened. Adding the proper amount of sample to the oven allows for better and even heat transfer. Invest in a high-quality vacuum oven with pump Since laboratory drying ovens play an important role in laboratory testing, taking the time to choose which oven to purchase will save you money and worry. It starts with understanding what exactly you need your oven to do. There is no perfect oven, only one that suits your needs. This will help you determine which heating method is right for you, what materials, sizes and widths you need in the oven's construction, and how it manages its internal energy system. Check out XCH Biomedical for high quality, durable and reliable laboratory vacuum oven. If you are still not sure which oven to buy for your laboratory, you can easily consult XCH Biomedical.
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  • Why choose XCH Biomedical as a laboratory equipment supplier
    Jan 13, 2023
    Does it matter where you buy your Temperature and humidity Equipment? Not all lab equipment suppliers are created equal. Here's why you should get a quote from XCH Biomedical: Competitive price Since XCH Biomedical acts as the manufacturer, you get the best price possible - unlike a distributor who buys a product and then charges you a premium. Not only do we offer great prices, but we also offer premium equipment packages. Give the right advice We work with a number of laboratory equipment consultants and construction and engineering firms to advise on new builds or refurbishments. But no matter what, we are your resource. Even after projects are complete, companies keep calling us for ideas and advice on equipment purchases and we are happy to help. 50+ years of experience We've sold thousands of pieces of lab equipment, which means we know how to avoid common challenges and pitfalls that can arise during the buying process. If you need help purchasing a single piece of equipment or an entire laboratory for new construction, let our experience save you time, money and hassle. No unexpected costs We believe in total transparency, which means we will not charge you anything during the process. Our pricing is pre-determined and our goal is to help you understand the complete cost from ordering and delivery to setup and training. Training Our experienced, factory-trained representatives have the expertise to answer your questions and help you select exactly the products you need. They can also help you set up your equipment, provide training for you and your lab technicians, and answer questions throughout the product's lifecycle. One stop supplier With our extensive experience in laboratory equipment, including stability chamber, high and low temperature test chamber, Lab Biochemical Incubator, lab drying oven, etc. customer service is our top priority. Whether your laboratory requires a single replacement unit or an entire equipment package, XCH Biomedical is your one-stop supplier for all your laboratory equipment needs.
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  • Stability Test Standard
    Jan 06, 2023
    In Stability Testing - An Overview, we look at Stability Testing Requirements - Chamber Selection, Validation Requirements, IQOQPQ and IPV Considerations. In order to demonstrate the shelf life of a drug in a certain market, the manufacturer must store it at the relevant temperature and humidity for a specified period of time. This is done in what is also known as a stabilization chamber. Regulatory agencies in each market, such as FDA in the US, HPRA in Ireland, specify the temperature and humidity conditions that should be used and how long samples should be stored, such as a minimum of 6 to 12 months. During this time, samples were tested and their potency and degradation measured and recorded. This is called a stability test. The most common conditions are 25°C/60%RH. For new products, accelerated conditions may be 40°C/75%RH. Other conditions include 30°C/65%RH, 30°C/35%RH and 25°C/40%RH. For products intended to be stored in a blood bank Refrigerator, another condition is 5°C ±3°C. For products intended to be stored in a refrigerator, the test condition is -20°C ±5°C. ICH, the International Conference on Harmonization of Technical Requirements for the Registration of Pharmaceuticals for Human Use, has developed rules for running stability tests. ICH Q1A states that during stability testing, conditions should be kept constant at ±2°C and ±5%RH. Also, if these conditions are not met for more than 24 hours, the test may need to be extended, creating a lot of paperwork. If conditions deviate from ±2°C/±5%RH, even for a short period of time should be accounted for. Probably due to the door opening to "pull" the sample. Events like this are usually logged in the room log. If no explanation is apparent, it may be necessary to seek assistance from a service engineer. In the event of a failure in the laboratory, a quick response from the supplier is required and although he should stock major spare parts, the auditor would also like to have some stocked on-site as well. It is also recommended to have redundancy, ie another room on site as a backup. The chamber must be fully validated and ready for use. Photostability Test Chamber To demonstrate shelf life under ambient light conditions, samples may be exposed to precise doses of UV and visible light in specially designed chambers. ICH Q1B specifies temperature control to prevent localized hot spots. Surveillance and 21 CFR Part 11 Indoor conditions should be independently monitored. This usually requires temperature and humidity transmitters connected to the recording system. In the Photostability chamber temperature, UV and visible light intensities will be recorded. This system must comply with the regulations of 21 CFR part 11 in the United States, whether it is a paper recorder or a computer system. 21 CFR Part 11 states that all related data collection and storage systems must be designed to prevent counterfeiting, corruption, untraceable alteration, or loss of data. In the case of computer systems, formal testing (IQOQ-Installation Qualification, Operation Qualification) should be performed to demonstrate compliance. Stability chamber Qualification Likewise, formal testing (IQOQ and PQ performance qualification) must be performed on new Stability chamber. During its useful life it should be maintained regularly (usually annual preventive maintenance service and calibration checks) and preferably mapped with several probes per year (IPV - Instrument Performance Verification). PQ and IPV typically require at least one 24-hour surveillance run, empty, loaded, or both. During this run, conditions must be shown to remain within ±2°C, ±5%RH of the set point. Test equipment used for these tests must be traceably calibrated at least annually and meet the IQOQ standards of 21 CFR P11.
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  • Contamination Control in Medical Laboratories
    Dec 27, 2022
    In a medical laboratory, the risk of contamination of cell cultures is incalculable – no matter how meticulous the work. It is certainly not unheard of for risks to be miscalculated, and contamination often results in culture loss. Therefore, in this blog, we would like to shed light on how to systematically detect and avoid contamination in cell lines. Every medical laboratory is under threat day in and day out Microbial contamination in cell cultures—including those purchased from third parties—is not uncommon in laboratories. In fact, the opposite is true: Many cell lines grown in the laboratory are infected with mycoplasma. Tiny fungal spores are ubiquitous and can spread through the air. Of course, when working in a sterile environment, there is room for human error. It's easy to make a mistake. Horror scenarios in cell culture labs - contamination of all types: Microbial contamination (bacteria, mycoplasma, fungi, yeast, etc.) virus contamination protein contamination (prions) Chemical contamination (leachables and extractables from plastics, heavy metals, etc.) Cross-contamination with other cell cultures Where does pollution come from? 1. How "clean" is the original culture? Problems often start with the source material. Even with all possible efforts in the production of media, some materials cannot be rendered completely sterile. Therefore, there is always a risk of mycoplasma escaping the sterile filter. Prions can even survive steam sterilization at 121 °C. 2. Is the working laboratory really a sterile environment? One of the main causes of laboratory contamination is the human body. For example, many instances of cross-contamination could be avoided if lab technicians avoided handling multiple production lines at the same time on the sterile bench. One culture can quickly infect another if the liquid is not handled properly. Also, rushing things through is the worst enemy of dull work. The door of the laboratory incubator should not be opened without reason, and of course it should not be left open for a long time. No matter how much time pressure they may be under, lab technicians should only work on one cell line at a time. When unpacking disposable pipettes under the bench, the cap must be set aside after unscrewing. 3. Are you using the correct laboratory equipment? Of course, even equipment used in medical laboratories is entirely possible to cause contamination in cell culture. Therefore, we recommend: Use plasticizer-free plastic containers Choose a suitable location for the incubator (location near the washbasin may lead to soap contamination) Use incubator accessories made of sterilized copper When antibiotics are used, antibiotic-free lines should be bred from time to time. (This is because antibiotics can mask the contamination and the infection can spread.) What investigative methods can be used to track which infections? One of the most dangerous things about mycoplasma infections is that they often go undetected for a long time. In principle, pollution events can be controlled and tracked by a variety of methods, some very sophisticated and others less so. An experienced lab technician can tell if cross-contamination has occurred simply by looking under a microscope. If we extract all the DNA from a cell culture, the PCR method can be used to detect its mycoplasma DNA content. Laboratories performing viral transduction or bioassays should also check for viral contamination. Laboratories manufacturing drugs for novel therapeutics should check for low risk of bacteria, spores, fungi, mycoplasma, HIV, HCV, and BSE. How should pollution be dealt with? Every instance of contamination must be documented and graded. If nothing else, medical labs that keep pollution problems under wraps are jeopardizing their good reputations. Of course, special cleaning measures must also be taken in case of contamination: in the case of fungal infections, it is advisable to check that the laboratory is regularly disinfected with an alcohol-based agent As a general rule, regular spray or wipe disinfection of the scientific incubator interior with an alcohol-based solution helps to avoid contamination Monthly hot air sterilization is standard medical practice in many laboratories For sensitive stem cells, it is only in rare cases that infected cell lines can be treated with antibiotics. In most cases the solution is expensive - the culture has to be scrapped and the work has to be started from scratch in conclusion: Being able to consistently detect, validate and deal with contamination is absolutely essential, especially in medical laboratories that work with highly sensitive stem cells and do not use antibiotics. Transparent monitoring is essential. Covering up contamination or allowing it to spread only increases the danger and is unnecessary. The Constant Temperature Incubator should always be the safest component of the entire process step; if a sample is contaminated, then in most cases this occurs either upstream or downstream of the cooling incubator cultivation.
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  • Thchamber Drying Chamber Guide
    Dec 14, 2022
    Drying ovens are used in laboratories or industry to heat materials and remove their moisture content. It is usually used where a drying process is required, such as food, agricultural products, pharmaceuticals, etc. There are different types of drying ovens on the market, such as hot air oven, vacuum oven with pump, dry heat oven, etc. Drying ovens are used to speed up the drying process by creating optimal evaporation conditions. The material is dried by convective heating that circulates air around the material by using a hot air oven. This type of drying is effective and efficient for large batches. Drying Oven: Definition A drying oven is an oven used to remove moisture from objects or materials. The stove uses heat to evaporate water and vents the resulting steam outside. They are often used on materials that are sensitive to water damage, such as electronic components or chemicals. You can also use them to remove moisture from food to extend its shelf life. Some ovens are also equipped with a dehumidifier, which helps to further reduce the relative humidity inside the oven. By keeping humidity low, the drying process can occur faster and more efficiently. Drying Oven application: Drying chambers are used in different applications such as scientific research, food processing, agriculture and many more. The sample under test is exposed to a preset temperature for a specific time set by the user. It is used for drying chemicals, pharmaceuticals and other substances. Aging or tempering of plastic and electronic components can also be done in these ovens. In agriculture, seeds and crop products are dried using laboratory ovens for longer storage. Stability testing in the food industry is done using these ovens. Drapes and gloves are also heated in these ovens so they can be sterilized. Drying Oven working process: This equipment is an oven used to remove moisture from materials. The chamber walls are exposed to a specific temperature at atmospheric pressure. Thermal energy enters the chamber load naturally or through forced convection and radiation. The surface heating system provides support from the back of the interior walls. The drying process goes faster as the temperature and air dries. The drying oven dries and heats the sample at the same time, allowing the sample to dry quickly and evenly. This process helps to measure the moisture content of the product being manufactured. Liquid content and content volatiles are removed during the drying process. Drying chambers are used in different applications such as scientific research, food processing, agriculture and many more. The weighed sample is exposed to a preset temperature for a specific time set by the user. You can find the resulting loss on drying with the aid of percent weight loss or moisture analysis. These methods are used to remove moisture from food. Dehydration helps preserve food and makes it easier to carry when traveling. Ovens of different capacities and dimensions are available upon request. Please contact vacuum oven manufacturer thchamber with your drying cabinet needs and one of our experts will be in touch shortly. Get in touch now!
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  • About Environmental chambers - XCH Biomedical
    Dec 05, 2022
    Environmental chambers have been used to research products for decades, with countless applications in aerospace, artificial intelligence, automotive, electronics, solar cells, medical, industrial, and consumer research. In these industries, samples or materials to be tested must be exposed to defined changes in environmental factors in order to study their effects and even prepare for future research. The conditions that an environmental chamber can replicate are: temperature set point (or change), relative humidity or moisture in the form of rain, electromagnetic radiation, vibration, weathering, salt spray, sun exposure/UV degradation, and vacuum. The type of testing involved will determine the chamber type; chambers come in a variety of sizes and are designed with different features and options. Environmental chamber humidity control and specimen incubators Prepared specimens or materials are placed in chambers and then subjected to specified levels of environmental stimuli to determine how responsive they are. The resulting by-products were also measured and studied. Chamber of Commerce Type Humidity or temperature chambers are used for climatic testing, while vibration and stress chambers are often used for mechanical testing, such as evaluating a product's performance under vibration or shock. "Pressure" is usually tested using a pressure variable or a vacuum. Stress and vibration chambers are also used in electronics, solar or fuel cells, and automotive products, where testing requirements are very demanding. The goal is to go beyond "normal" to measure the limitations of materials. Highly Accelerated Life Testing, formally known as HALT testing, is used to discover potential defects and ultimately improve products at the design stage. The chamber will simulate various stimuli such as vibration, aging, humidity, voltage and thermal cycling, which can cause many flaws in design or production. Instead, a compliance test known as HASS (Highly Accelerated Stress Screening) is performed during production to identify defects prior to commercialization. These tests use temperature and humidity variables to find potential defects. Environmental test chambers for manufacturing and production have been used for decades and are capable of generating pressures far greater than normal for commercial products. chamber design Environmental chambers can be designed as walk in environmental chamber, bench-top, floor-standing, reach-in or drive-in configurations. Depending on the function they perform, they can range in size from portable devices to gigantic rooms, such as the vacuum chamber at NASA's Space Power Facility, which is the largest of its kind. Floor-standing and table-top darkrooms are the most widely used. While most chambers are made of steel, the materials used for the inner and outer walls vary by application. When used in food packaging or pharmaceutical applications, the chamber may have glass doors for visual access. The intended application of the chamber also affects the types of heaters, coolers, condensers, evaporators, controllers, sensors and other modules used. Newer test chambers have evolved to keep pace with product testing requirements, such as those used in biological and military applications. These chambers are usually custom-made to meet all necessary environmental testing requirements and the equipment used for the measurements is very accurate and reliable. The newer design of the photostable stability chambers in pharmaceutical has a smaller footprint and is easier to handle than its predecessor. Their user interface resembles a touchscreen Windows monitor rather than traditional scrolling electronics. If they are network enabled, they can be programmed and operated online
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